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RED YEAST RICE

Monascus purpureus Went

Description

Monascus purpureus Went is a filamentous fungus whose asexual reproduction is carried out by conidia germination and filament formation that constitute a mycelium, which is white initially but then it acquires a color that ranges from pink to orange-red due to the biosynthesis of colored pigments (main pigments: yellow monascin and ankaflavin, orange rubropunctatin and monascorubin, and red rubropunctamine and monascorubramine) originated by the densification of polyketides and fatty acids.

Under some conditions, the growth of this fungus on the rice grain is produced by fermentation, which gives a red coloring to the rice because of the synthesis of red, yellow and orange pigments. At present, red yeast rice is obtained through controlled culture of selected strains of this fungus on rice.

Part used

The yeast Monascus purpureus grows on rice. Both the isolated yeast or “red yeast of rice” and the rice with the yeast or “red yeast rice” are commercialized. It is important these products specify their content in monacolin K.

Indications

> It is recommended for patients with primary hypercholesterolemia together with the proper dietary treatment.
> Prevention of cardiovascular diseases.

Bibliography

Yang CW, Mousa SA. The effect of red yeast rice (Monascus purpureus) in dyslipidemia and other disorders. Complement Ther Med. 2012; 20 (6): 466-74. 

Chien-Fang Huang ,Tsai-Chung Li, Cheng-Chieh Lin et al. Efficacy of Monascus purpureus Went rice on lowering lipid ratios in hypercholesterolemic patiens. Eur J Cardiovasc Prev Rehabil. 2007 Jun;14(3):438-40

Xiong X, Wang P, Li X, Zhang Y, Li S. The effects of red yeast rice dietary supplement on blood pressure, lipid profile, and C-reactive protein in hypertension: A systematic review. Crit Rev Food Sci Nutr. 2017; 57 (9): 1831-1851.

Peng D, Fong A, Pelt AV.Original Research: The Effects of Red Yeast Rice Supplementation on Cholesterol Levels in Adults. Am J Nurs. 2017 Aug; 117(8):46-54

Lin CC, Li TC, Lai MM. Efficacy and safety of Monascus purpureus Went rice in subjects with hyperlipidemia. Eur J Endocrinol. 2005; 153 (5): 679-86.

Gheith O, Sheashaa H, Abdelsalam M, Shoeir Z, Sobh M. Efficacy and safety of Monascus purpureus Went rice in subjects with secondary hyperlipidemia. Clinical and experimental nephrology, 2008, 12(3), 189‐194.

Nguyen T, Karl M, Santini A. Red Yeast Rice. Foods. 2017 Mar 1; 6(3).


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